General Information

  • ID:  hor000882
  • Uniprot ID:  F5XVE7(34-60)
  • Protein name:  Ci-GALP
  • Gene name:  ci-galp
  • Organism:  Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
  • Family:  Galanin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Ciona (genus), Cionidae (family), Phlebobranchia (order), Ascidiacea (class), Tunicata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0005179 hormone activity
  • GO BP:  GO:0007165 signal transduction
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  PFRGQGGWTLNSVGYNAGLGALRKLFE
  • Length:  27(34-60)
  • Propeptide:  MNSFGRYTFSLAVVLYISIVLCAENSEAATAKRPFRGQGGWTLNSVGYNAGLGALRKLFEKRDGSSLDVESMPLDNEEMENLAKDFALFLEVKESGLLGPRMLRCILSRNDQVMDSMSEM
  • Signal peptide:  MNSFGRYTFSLAVVLYISIVLC
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-F5XVE7-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000882_AF2.pdbhor000882_ESM.pdb

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Physical Information

Mass: 337324 Formula: C133H202N38O36
Absent amino acids: CDHIM Common amino acids: G
pI: 10.45 Basic residues: 3
Polar residues: 11 Hydrophobic residues: 10
Hydrophobicity: -22.22 Boman Index: -2586
Half-Life: >20 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: ? Aliphatic Index 75.93
Instability Index: 1141.48 Extinction Coefficient cystines: 6990
Absorbance 280nm: 268.85

Literature

  • PubMed ID:  21467196
  • Title:  Peptidomic Analysis of the Central Nervous System of the Protochordate, Ciona Intestinalis: Homologs and Prototypes of Vertebrate Peptides and Novel Peptides